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Good morning, Boston. Sports betting begins today in Mass., and here are the five things you need to know in Boston business news to start your workday.

Two more Boston-area biotechs shut down

Rowan Walrath reports that two more local biotech startups have shut down in the past week — totaling at least nine since the start of 2022.

Out with the old BPDA … in with the new 'BPDA'?

Mayor Michelle Wu has put forward legislation to abolish the agency now known as the Boston Planning and Development…

Five Star Bank is expanding its boundaries by relying on experienced commercial banking teams to lead the way in new markets.

The 40 surgeons who plan to operate at the Kaleida Health/UBMD site expect to do more than 11,000 procedures annually, making it one of the top five largest local sites for volume.

The 2023 Leaders in Corporate Citizenship honorees will be celebrated at an event on Feb. 16.

Myosana's first target is Duchenne muscular dystrophy, a genetic disorder that leads to muscle degeneration.

The hospital system said the center maintains a low volume of births with an “unusually high-cost model.”

PBN chatted with Dr. Naoto Ueno recently about his transition, hiring and funding goals for the UH Cancer Center.

Amgen Inc. is laying off 300 U.S. employees, citing “industry headwinds” amid a down market for biopharma. But the company won't say where exactly those employees are based.

The company won't launch its lookalike version of AbbVie's Humira until July, though it was approved by the FDA in December 2021.

The bills would enable them to cover the cost of dispensing drugs and prevent more pharmacies from closing, advocates say.